Endocrine Abstracts

The metabolic syndrome (MetS) is a constellation of physiological and biochemical abnormalities characterized by obesity, hyperglycaemia, elevated triglycerides and decreases in high density lipoprotein cholesterol (HDL-C), and hypertension. The MetS promotes atherosclerosis, and increases the risk of developing diabetes and cardiovascular disease (CVD), as well as rates of mortality. Thus, it has become one of the major public health challenges worldwide. In Tunisia, few stud...

Introduction: Mitochondrial diabetes (MD) is characterized by a broad spectrum of phenotypic and genotypic involvement. Through a cohort study of 40 patients with DM, we tried to correlate this diversity of phenotypic expression with the biomolecular substratum of the mitochondrial genome in the Tunisian population.Results: Epidemiologically and anthropometrically, our series fits the literature data with age at 31.6 years (5–52), female predominanc...